Coordination of erythropoiesis by the transcription factor c-Myb

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چکیده

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Coordination of erythropoiesis by the transcription factor c-Myb.

The involvement of the transcription factor c-Myb in promoting the proliferation and inhibition of erythroid cell differentiation has been established in leukemia cell models. The anemia phenotype observed in c-myb knockout and knockdown mice highlights a critical role for c-Myb in erythropoiesis. However, determining the reason for the failure of erythropoiesis in these mice and the precise fu...

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ژورنال

عنوان ژورنال: Blood

سال: 2006

ISSN: 0006-4971,1528-0020

DOI: 10.1182/blood-2005-07-2968